Everybody must do yoga and meditation. In this house we say how you doin pivot pivot pivot and we were on a break shirt. Over long periods of time, the body’s efforts to reduce inflammation end up suppressing the immune system. Chronic stress causes cortisol levels to keep rising, but over time it becomes much less effective in managing inflammation. Immune cells become insensitive to cortisol, allowing the immune system to become dysregulated and enabling runaway inflammation.